Midfielder Alexander Hleb returns from a virus, but Theo Walcott is left out.
PSV Eindhoven striker Jefferson Farfan is a major doubt with a foot injury but right-back Jan Kromkamp should be fit despite missing training on Monday.
The injuries to Eboue and Hoyte could mean that William Gallas will start in the Arsenal defence in only his second game back from his lengthy lay-off.
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